Blasted Pancreas - Hematological Malignancy

A brainstem glioma is a cancerous glioma tumour in the brainstem. They are most often found in children under the age of twenty. The cause is still unknown and is not often treated with neurosurgery due to complications in vital parts of the brain.

Cystic Fibrosis is a hereditary disease that affects the entire body, causing progressive disability and early death. There is no cure for cystic fibrosis, and most affected individuals die young from lung failure. Cystic fibrosis is caused by a mutation in the cystic fibrosis transmembrane conductance rogulator (CFTR) gene.

Hemangiosarcoma is a rare, rapidly growing, highly invasive variety of cancer. It is a bloodfed sarcoma. Blood vessels grow directly into the humour and it is typically filled with blood. A frequent cause of death is the rupturing of this tumour, causing the victim to rapidly bleed to death.

Hematological malignancy is malignant neoplasms that affect blood, bone marrow and lymph nodes. May derive from either the two major blood cell lineages: myeloid and lymphoid cell lines.

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Lymphangiosarcoma is a rare malignant tumour which occurs in long-standing cases of primary or secondary lymphedema. It involves either the upper or lower lymphedemateous extremities but is most common in upper extremities. The sarcoma first appears as a bruise mark, a purplish discolourisation or a tender skin nodule in the extremity, typically on the anterior surface. It progresses to an ulcer with crusting, and finally to an extensive necrosis involving the skin and subcutaneous tissue. It metastasizes quickly.

Lymphoblasts are immature cells which typically differentiate to form mature lymphocytes. Normally lymphoblasts are found in the bone marrow, but in acute lymphoblastic leukemia, lymphoblasts proliferate uncontrollably and are found in large numbers in the peripheral blood.

Nephroblastoma is a malignant tumour of the kidneys that typically occurs in children, rarely in adults. Containing metanephric blastema, stromal and epithelial derivatives. Characteristic is the presence of abortive tubules and glomeruli surrounded by a spindled cell stroma. The stroma may include striated muscle, cartilage, bone, fat tissue, fibrous tissue. The tumour is compressing the normal kidney parenchyma.

Polycythemia vera is a blood disorder in which the bone marrow makes too many red blood cells. Polycythemia vera may also result in the overproduction of white blood cells and platelets. Most of the health concerns associated with polycythemia vera are caused by a blood-thickening effect that results from an overproduction of red blood cells.

Tuberculosis is a common and often deadly infectious disease caused by mycobacteria, usually Mycobacterium tuberculosis in humans. Tuberculosis usually attacks the lungs but can also affect other parts of the body. It is spread through the air, when people who have the disease cough, sneeze, or spit. Most infections in humans result in an asymptomatic, latent infection, and about one in ten latent infections eventually progresses to active disease, which, if left untreated, kills more than 50% of its victims.